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spio contrast agent ferex  (BioPAL Inc)

 
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    BioPAL Inc spio contrast agent ferex
    <t>Superparamagnetic</t> <t>iron</t> <t>oxide</t> <t>(SPIO)</t> contrast enhancement of acute vocal fold injury. (A) T2- and T2*-weighted (T2W, T2*W) coronal images of the rat abdomen and neck, acquired in vivo at 4.7 T with and without intravenous SPIO contrast enhancement. Red asterisks indicate livers, red arrows indicate larynges. (B) T2W axial and coronal images of the rat larynx, 5 days following right-sided vocal fold mucosal injury. Images were acquired ex vivo at 4.7 T, with and without (pre-explant) intravenous SPIO contrast enhancement. Red arrows indicate hypointense mucosal lesions. (C) Pseudocolored volume renders of the vocal fold mucosal lesions shown in B. Lesions are red; thyroid (brown), cricoid (green) and arytenoid (cyan) cartilages are shown for anatomic orientation. (D) Effect of contrast enhancement on vocal fold mucosal lesion volume (mean±s.e.m.); n.s., no significant difference ( P >0.01), calculated using a Student's t -test. (E) H&E-, Prussian Blue- and CD68-stained vocal fold coronal sections, 5 days following mucosal injury. Black arrows indicate blood (red) and hemosiderin (brown) in the H&E-stained sections and ferric iron (blue) in the Prussian Blue-stained sections; white arrows indicate CD68 + cells (green) in the immunosections (nuclei are counterstained blue). Scale bars: 100 µm. Data represent n =5 animals per experimental condition in A-E, with the exception of the injury+SPIO images and render in panels B and C; these data represent n =2/5 animals in which contrast enhancement was associated with larger lesion volumes. R, right; L, left.
    Spio Contrast Agent Ferex, supplied by BioPAL Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/spio contrast agent ferex/product/BioPAL Inc
    Average 90 stars, based on 1 article reviews
    spio contrast agent ferex - by Bioz Stars, 2026-06
    90/100 stars

    Images

    1) Product Images from "High- and ultrahigh-field magnetic resonance imaging of naïve, injured and scarred vocal fold mucosae in rats"

    Article Title: High- and ultrahigh-field magnetic resonance imaging of naïve, injured and scarred vocal fold mucosae in rats

    Journal: Disease Models & Mechanisms

    doi: 10.1242/dmm.026526

    Superparamagnetic iron oxide (SPIO) contrast enhancement of acute vocal fold injury. (A) T2- and T2*-weighted (T2W, T2*W) coronal images of the rat abdomen and neck, acquired in vivo at 4.7 T with and without intravenous SPIO contrast enhancement. Red asterisks indicate livers, red arrows indicate larynges. (B) T2W axial and coronal images of the rat larynx, 5 days following right-sided vocal fold mucosal injury. Images were acquired ex vivo at 4.7 T, with and without (pre-explant) intravenous SPIO contrast enhancement. Red arrows indicate hypointense mucosal lesions. (C) Pseudocolored volume renders of the vocal fold mucosal lesions shown in B. Lesions are red; thyroid (brown), cricoid (green) and arytenoid (cyan) cartilages are shown for anatomic orientation. (D) Effect of contrast enhancement on vocal fold mucosal lesion volume (mean±s.e.m.); n.s., no significant difference ( P >0.01), calculated using a Student's t -test. (E) H&E-, Prussian Blue- and CD68-stained vocal fold coronal sections, 5 days following mucosal injury. Black arrows indicate blood (red) and hemosiderin (brown) in the H&E-stained sections and ferric iron (blue) in the Prussian Blue-stained sections; white arrows indicate CD68 + cells (green) in the immunosections (nuclei are counterstained blue). Scale bars: 100 µm. Data represent n =5 animals per experimental condition in A-E, with the exception of the injury+SPIO images and render in panels B and C; these data represent n =2/5 animals in which contrast enhancement was associated with larger lesion volumes. R, right; L, left.
    Figure Legend Snippet: Superparamagnetic iron oxide (SPIO) contrast enhancement of acute vocal fold injury. (A) T2- and T2*-weighted (T2W, T2*W) coronal images of the rat abdomen and neck, acquired in vivo at 4.7 T with and without intravenous SPIO contrast enhancement. Red asterisks indicate livers, red arrows indicate larynges. (B) T2W axial and coronal images of the rat larynx, 5 days following right-sided vocal fold mucosal injury. Images were acquired ex vivo at 4.7 T, with and without (pre-explant) intravenous SPIO contrast enhancement. Red arrows indicate hypointense mucosal lesions. (C) Pseudocolored volume renders of the vocal fold mucosal lesions shown in B. Lesions are red; thyroid (brown), cricoid (green) and arytenoid (cyan) cartilages are shown for anatomic orientation. (D) Effect of contrast enhancement on vocal fold mucosal lesion volume (mean±s.e.m.); n.s., no significant difference ( P >0.01), calculated using a Student's t -test. (E) H&E-, Prussian Blue- and CD68-stained vocal fold coronal sections, 5 days following mucosal injury. Black arrows indicate blood (red) and hemosiderin (brown) in the H&E-stained sections and ferric iron (blue) in the Prussian Blue-stained sections; white arrows indicate CD68 + cells (green) in the immunosections (nuclei are counterstained blue). Scale bars: 100 µm. Data represent n =5 animals per experimental condition in A-E, with the exception of the injury+SPIO images and render in panels B and C; these data represent n =2/5 animals in which contrast enhancement was associated with larger lesion volumes. R, right; L, left.

    Techniques Used: In Vivo, Ex Vivo, Staining



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    spio contrast agent ferex  (BioPAL Inc)
    90
    BioPAL Inc spio contrast agent ferex
    <t>Superparamagnetic</t> <t>iron</t> <t>oxide</t> <t>(SPIO)</t> contrast enhancement of acute vocal fold injury. (A) T2- and T2*-weighted (T2W, T2*W) coronal images of the rat abdomen and neck, acquired in vivo at 4.7 T with and without intravenous SPIO contrast enhancement. Red asterisks indicate livers, red arrows indicate larynges. (B) T2W axial and coronal images of the rat larynx, 5 days following right-sided vocal fold mucosal injury. Images were acquired ex vivo at 4.7 T, with and without (pre-explant) intravenous SPIO contrast enhancement. Red arrows indicate hypointense mucosal lesions. (C) Pseudocolored volume renders of the vocal fold mucosal lesions shown in B. Lesions are red; thyroid (brown), cricoid (green) and arytenoid (cyan) cartilages are shown for anatomic orientation. (D) Effect of contrast enhancement on vocal fold mucosal lesion volume (mean±s.e.m.); n.s., no significant difference ( P >0.01), calculated using a Student's t -test. (E) H&E-, Prussian Blue- and CD68-stained vocal fold coronal sections, 5 days following mucosal injury. Black arrows indicate blood (red) and hemosiderin (brown) in the H&E-stained sections and ferric iron (blue) in the Prussian Blue-stained sections; white arrows indicate CD68 + cells (green) in the immunosections (nuclei are counterstained blue). Scale bars: 100 µm. Data represent n =5 animals per experimental condition in A-E, with the exception of the injury+SPIO images and render in panels B and C; these data represent n =2/5 animals in which contrast enhancement was associated with larger lesion volumes. R, right; L, left.
    Spio Contrast Agent Ferex, supplied by BioPAL Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/spio contrast agent ferex/product/BioPAL Inc
    Average 90 stars, based on 1 article reviews
    spio contrast agent ferex - by Bioz Stars, 2026-06
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Superparamagnetic iron oxide (SPIO) contrast enhancement of acute vocal fold injury. (A) T2- and T2*-weighted (T2W, T2*W) coronal images of the rat abdomen and neck, acquired in vivo at 4.7 T with and without intravenous SPIO contrast enhancement. Red asterisks indicate livers, red arrows indicate larynges. (B) T2W axial and coronal images of the rat larynx, 5 days following right-sided vocal fold mucosal injury. Images were acquired ex vivo at 4.7 T, with and without (pre-explant) intravenous SPIO contrast enhancement. Red arrows indicate hypointense mucosal lesions. (C) Pseudocolored volume renders of the vocal fold mucosal lesions shown in B. Lesions are red; thyroid (brown), cricoid (green) and arytenoid (cyan) cartilages are shown for anatomic orientation. (D) Effect of contrast enhancement on vocal fold mucosal lesion volume (mean±s.e.m.); n.s., no significant difference ( P >0.01), calculated using a Student's t -test. (E) H&E-, Prussian Blue- and CD68-stained vocal fold coronal sections, 5 days following mucosal injury. Black arrows indicate blood (red) and hemosiderin (brown) in the H&E-stained sections and ferric iron (blue) in the Prussian Blue-stained sections; white arrows indicate CD68 + cells (green) in the immunosections (nuclei are counterstained blue). Scale bars: 100 µm. Data represent n =5 animals per experimental condition in A-E, with the exception of the injury+SPIO images and render in panels B and C; these data represent n =2/5 animals in which contrast enhancement was associated with larger lesion volumes. R, right; L, left.

    Journal: Disease Models & Mechanisms

    Article Title: High- and ultrahigh-field magnetic resonance imaging of naïve, injured and scarred vocal fold mucosae in rats

    doi: 10.1242/dmm.026526

    Figure Lengend Snippet: Superparamagnetic iron oxide (SPIO) contrast enhancement of acute vocal fold injury. (A) T2- and T2*-weighted (T2W, T2*W) coronal images of the rat abdomen and neck, acquired in vivo at 4.7 T with and without intravenous SPIO contrast enhancement. Red asterisks indicate livers, red arrows indicate larynges. (B) T2W axial and coronal images of the rat larynx, 5 days following right-sided vocal fold mucosal injury. Images were acquired ex vivo at 4.7 T, with and without (pre-explant) intravenous SPIO contrast enhancement. Red arrows indicate hypointense mucosal lesions. (C) Pseudocolored volume renders of the vocal fold mucosal lesions shown in B. Lesions are red; thyroid (brown), cricoid (green) and arytenoid (cyan) cartilages are shown for anatomic orientation. (D) Effect of contrast enhancement on vocal fold mucosal lesion volume (mean±s.e.m.); n.s., no significant difference ( P >0.01), calculated using a Student's t -test. (E) H&E-, Prussian Blue- and CD68-stained vocal fold coronal sections, 5 days following mucosal injury. Black arrows indicate blood (red) and hemosiderin (brown) in the H&E-stained sections and ferric iron (blue) in the Prussian Blue-stained sections; white arrows indicate CD68 + cells (green) in the immunosections (nuclei are counterstained blue). Scale bars: 100 µm. Data represent n =5 animals per experimental condition in A-E, with the exception of the injury+SPIO images and render in panels B and C; these data represent n =2/5 animals in which contrast enhancement was associated with larger lesion volumes. R, right; L, left.

    Article Snippet: To reduce T2 relaxation time and evaluate its effect on tissue contrast, we injected a subset of rats in the 5 day post-injury group with intravenous SPIO contrast agent [200 μmol Fe/kg Ferex (∼5 nm iron core size, ∼50-150 nm colloidal matrix size), BioPal, Worcester, MA], 24 h before image acquisition.

    Techniques: In Vivo, Ex Vivo, Staining